Effects of Genetically Modified (GM) Soybean and Tempe Consumption on Blood Profile, Malondialdehyde (MDA) Level and Superoxide Dismutase (SOD) Activity of Sprague-Dawley Rats
Keywords:
GM Soybean, Tempe, MDA, SOD, Sprague-Dawley ratsAbstract
Tempe, an Indonesian traditional food, is the product of the fermentation of soybean by the mold Rhizopus oligosporus. Tempe and other soyfoods products such as tofu, soy sauce and soymilk has long been a part of traditional Indonesian diets, consumed at daily basis and become important protein sources for most population. On the other side, soybean consumption requirements are fulfilled with imported soybeans which mostly are cultivated by genetic modification (Genetically Modified Foods or GM Foods).
References
Badan Pusat Statistik. 2013. Berita Resmi Statistik : Produksi Padi, Jagung, Dan Kedelai, No. 45/07/Th.XVI. 1 Juli 2013.
Astawan M. 2008. Khasiat Warna-Warni Makanan. Jakarta (ID): Gramedia Pustaka Utama
Anderson JW, Johnstone BM, Cook-Newell ME. 1995. Meta-analysis of the effects of soy protein intake on serum lipids. Journal Medical. Vol 33 No. 2 : 276-282
Lichtenstein AH. 1998. Soy protein, isoflavones and cardiovascular disease risk. Journal Nutr. Vol 128. No.2: 1589-1592
Astuti S. 2008. Isoflavon kedelai dan potensinya sebagai penangkap radikal bebas. Jurnal Teknologi Industridan Hasil Pertanian. Vol.13 No.2 :126-136
Messina M. 2010.Insights Gained from 20 Years of Soy Research.Journal Nutr. 140: 2289S-2295S.
Hardinsyah.
Association of Official Analytical Chemistry (AOAC). 2005. Official Method of Analysis. Association of Official Analytical Chemistry, Maryland,USA.
Zhu Y, Li D, Wang F, Yin J, Jin H. 2004. Nutrional assesment and fate of DNA of soybean meal from roundup ready or conventional soybeans using rats. Archieves of Animal Nutrion, 58 (4): 295-310.
Turner AH, Pike MJ, Francis MA. 2008. Haematology what does your blood test mean ?. Workshop at RMIT
Bastiansyah E. 2008. Panduan Lengkap : Membaca Hasil Tes Kesehatan. Jakarta (ID): Penebar Plus.
Arrington LR. 1972.Animal Laboratory : In Introduction Laboratory Animal Science- The Breeding, Care and Management of Experimental Animals. Michigan (USA) : Interstate Printers & Publishers.
Effendi Z. 2003. Peranan leukosit sebagai anti inflamasi alergik dalam tubuh. [On-line]. Vol. 6. Available: http:// library. usu.ac.id/ download/fk/histologi-zukesti2.pdf. [Aug 1st, 2014]
Smith JB dan Mangkoewidjojo S. 1988. Pemeliharaan, Pembiakan dan Penggunaan Hewan Percobaan di Daerah Tropis. Tikus Laboratorium (Rattus norvegicus): 37-57. Depok (ID) : Universitas Indonesia.
Winandita, T.
Estridge B H, Reynolds A P, Walters N J. 2000. Basic Medical Laboratory Techniques 4 th Edition. United States of America: Thomson Learning.
Guyton AC. 1993. Sel Darah, Imunitas dan Pembekuan Darah. Di dalam: Buku Ajar Fisiologi Kedokteran. Edisi ke-7 bagian I. Ken Ariata Tengadi, dkk penerjemah. Jakarta (ID): Penerbit Buku Kedokteran, EGC. Terjemahan dari: Textbook of Medical Physiology
Booth C J, Brooks M B, Rockwell S. 2010. Spontaneous Coagulopathy in Inbred WAG/RijYcb Rats. J Comp Med Vol 60(1) : 25
Gu, C. Pan, H. Sun, Z. Qin, G. 2010.Effect of soybean variety on anti-nutritional factors content, and growth performance and nutrient metabolism in rat. Int. J. Mol. Sci.11, 1048-1056; DOI:10.3390/ijms11031048
Sacher RA, Pherson ARM. 2004. Tinjauan Klinis Hasil Pemeriksaan Laboratorium. Ryan, penerjemah; Huriawati H, editor. Jakarta (ID) : EGC. Terjemahan dari: Clinical Skills for Pharmacists. Ed ke-11.
Malole, M.B.M. and Pramono, C.S.U. 1989. Pengantar Hewan-Hewan Percobaan di Laboratorium. Bogor. Pusat Antara Universitas Bioteknologi IPB.
Sirait, J.
Erdmen JW. 2000. Soy protein and cardiovascular disease Risk. Journal Science.Vol 102. No. 3: 2555-2559
Ridges L, Sunderland R, Moerman K, Meyer B, Astheimer L, Howe P. 2001. Cholesterol lowering benefits of soy and linseed enriched foods. Journal ClinNutr. Vol10.No.3 : 204-211.
Bresnahan J. 2004. Biological and Physiological Data on Laboratory Animal.Jurnal 15.Kansas State University.
Schaasfma G. 2000. The Protein Digestibility
Herwiyarirasanta., BA, Eduardus. 2010. Effect of Black Soybean Extract Supplementation in Low Density Lipoprotein Level of Rats (Rattusnorvegicus) With High Fat Diet. Science Article Universitas Airlangga. Surabaya
Stockham SL, Scott MA. 2008. Fundamentals of Veterinary Clinical Pathology. 2nd edition. Lowa (USA). Blackwell Publishing.
Odden M C, Amadu AR,Ellen S, Lowell L O, Carmen A. 2014. Uric Acid Levels, Kidney Finction, and Cardiovascular Mortality in US Adults : National Health and Nutrition Examination Survey (NHANES) 1988-1994 and 1999-2002. American Journal of Kidney Diseases Vol 64(4) : 550-557.
Robert M. Blair, Susan E. Appt, Catherine Bennetau-Pelissero, Thomas B. Crarkson, Mary S. Anthony, Velerie Lamothe, Susan M. Potter. 2002. Dietary soy and soy isoflavones have gender specific effects on Plasma lipids and isoflavones in golden syrian F1B hybrid Hamster. J. Nutr. 132: 3585
Astuti S,Muchtadi D, Astawan M,Purwantara B,Wresdiyati T. 2009. Pengaruh Pemberian Tepung Kedelai Kaya Isoflavon Terhadap Kadar Malonaldehid (MDA), Aktivitas Superdioksida Dismutase (SOD) Testis dan Profil Cu,Zn-SOD Tubuli Seminiferi Testis Tikus Jantan. J.tekno dan Industri Pangan Vol XX(2):130-131.
Messina, Mar, Virginia Messina, Pauline Chan. 2011. Soyfoods, hyperuricemia and gout: A review of the epidemiologic and clinical data. Asia Pac J Clin Nutr 20 (3): 347
Lu F C. 2006. Toksikologi Ginjal. Dalam Toksikologi Dasar. Jakarta (ID): Universitas Indonesia Press. Pp 224-235.
Devasagayam T, Tilak J C, Boloor K, Ketaki S, Ghaskadbi S, Lele R D. 2004. Review Article : Free Radicals and Antioxidants in Human Health : Current Status and Future Prospects. Japi Vol 52 : 794-795
Halliwell B dan Gutterdige. 1997. Free Radicals in Biology and Medicine. Oxford University Press.
Downloads
Published
How to Cite
Issue
Section
License
Authors who submit papers with this journal agree to the following terms.
