Optimal conditions for gliotoxin production from Aspergillus fumigatus using solid state fermentation
Keywords:
Aspergillus fumigatus, Gliotoxin, optimum conditions, solid state fermentationAbstract
The ability of ten Aspergillus fumigatus isolates to produce gliotoxin was assessed by solid state fermentation using rice medium as a substrate. The results indicated that the AF-5 Aspergillus fumigatus isolate produced the most gliotoxin. The optimum conditions for gliotoxin production were a moisturising ratio of 5:1 (w: v) with distilled water, an inoculum size of 1.5 ml, containing 6
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