Lipoprotein Lipase, Amylase and Triglyceride Alteration: Lean Diabetic and Obese (Non-Diabetic) Patients
Keywords:
Lipase, amylase, triglyceride, obese, diabetes mellitusAbstract
Obesity, as well as type 2 diabetes mellitus, is a significant issue for health policy because it is so widespread in the population as a whole, and because of the high risk of complications it carries. Serum lipase and pancreatic amylase concentrations are used in conjunction with clinical findings to diagnose pancreatic disorders. The aim of this study was to differentiate the alterations in fasting dyslipidemia and serum levels of pancreatic enzymes in lean diabetics and non-diabetic obese. Triglyceride, lipase and amylase were measured in the serum collected from overnight fasting 300 volunteers those were separated into 3 groups; control group (non-diabetic and with normal weight), diabetics (normal weight) group and obese (non-diabetic) group. In this study, serum levels of triglyceride, amylase and lipase were significantly changed in obese group when compared to control group. But, only of triglyceride and amylase were increased significantly in diabetic group when compared to control group. On the other hand, serum lipase showed significant increase diabetic group when compared to obese group. In conclusion, serum triglyceride and amylase concentrations were higher in obese subjects than those with normal weight. The results of this study illustrated that serum lipase concentrations were decreased in obese subjects but increased in diabetic patients compared to the normal healthy subjects.
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