Family History of Non-communicable Disease and its Relationship in Acute Coronary Syndrome with or without Diabetes Mellitus

Abstract

Worldwide, non-communicable diseases which involve heart disease, diabetes mellitus and hypertension, represent a major risk factor that increases morbidity and mortality of acute coronary syndrome (ACS). The Objective of this study is to assess the Association of family history of non-communicable diseases in ACS patients with diabetes mellitus. This study is descriptive study of 175 ACS patients reported to the cardiology department in a tertiary care center in Ajman, UAE. Patient records were viewed on the computer database and all the necessary information required to achieve the objectives were extracted and filled in the checklist prepared. The data was analyzed by SPSS 20 and Chi square test was done to assess the association. The results shows that the non-communicable diseases reported were diabetes mellitus, hypertension and heart diseases. The degree of relation was divided into first and second degrees. The first degree of relation included (father, mother, brother, sister or more than one of them. The second degree of relation included (uncle, cousin, aunt, grandfather, grandmother etc.).

There were 11(91.7%) patients with first degree family history of DM and 1(8.3%) patient with second degree relation. Out of the 14 patients that gave positive family history of hypertension only one was second degree of relation and all the rest were first degree of relation. Regarding the most common non-communicable disease, heart disease, 18(94.7%) patients had first degree relatives and 1(5.3%) second degree relative with history of heart disease. As a conclusion we can say that among the ACS patients with family history of heart diseases, majority of them (94.7%) had in first degree relatives whereas in the case of family history of hypertension and diabetes, it was also highly reported in first degree relatives with 92.9% and 91.7% respectively. It was also found family history of DM has a major role for the occurrence of DM in ACS patients.