The Determination and Comparative Study of Basic Hormonal Assessment in Polycystic Ovary Syndrome (PCOS) Women Undergoing Assisted Reproduction Treatment in Southern Part of Nigeria
Abstract
Polycystic Ovarian Syndrome (PCOS) is a heterogenous disorder frequently diagnosed in women attending fertility clinics in Nigeria. it is characterized by anovulation, hyper androgenism and polycystic ovary, several factors have been associated with the pathophysiology of this disorder.A prospective cross-sectional study was conducted in four selected fertility clinics in South-South part of Nigeria. The purposive sampling technique was used to recruit participants. A total of 206 women were recruited in this study, 101 (49.1%) women fulfilled the Rotterdam criteria for the diagnosis of PCOS, while 105 women (50.9%) without PCOS were included as control. Biochemical hyper-androgenism as described by the Rotterdam criteria was observed in 69(68%) of women with PCOS, Elevated Anti-mullerian hormone (AMH) 87(86%) and elevated Luteinizing hormone (LH) 76(75%) were observed in women with PCOS.The aim of the study was to Determine and Compare levels of Luteinizing Hormone (LH) Follicle Stimulating Hormone (FSH) Anti-mullerian Hormone (AMH) Testosterone in the follicular fluid of women with PCOS undergoing Assisted Reproduction Treatment.
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