Diagnosing Multiple Endocrine Neoplasia Type1 in a Resource Limited Setting: A Case Report of Pancreatic Neuroendocrine Tumor Causing Gastric Outlet Obstruction
Keywords:
MEN1, pancreatic neuroendocrine tumor, primary hyperparathyroidism, Gastrinoma, endocrinopathyAbstract
Gastric outlet obstruction (GOO) is a narrowing of the pyloric outlet of the stomach due to benign or malignant disease processes. Pancreatic neuro endocrine tumor (NET) as a cause of GOO is a rare etiology. Pancreatic neuroendocrine tumors are underdiagnosed pre-operatively in resource limited settings. The following case report is about unusual presentation of GOO which was clinically and radiologically diagnosed to be a pancreatic neuroendocrine tumor, more specifically a Gastrinoma. Further evaluation of the patient revealed the presence of Primary Hyperparathyroidism (PHPT) too. The constellation of the two clinical diagnoses, led to the consideration of Multiple Endocrine Neoplasia type 1(MEN1) syndrome which has not been previously reported in Ethiopia. High index of clinical suspicion is important to diagnose the MEN1 related endocrine tumors.
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