Age and Sex Difference Between Low-grade and High-grade Colorectal Adenocarcinoma
AbstractColorectal cancer is currently the second leading cause of death in the world. Sex, age, and histological grading have interesting prognostic values for colorectal cancer to be studied further. The purpose of this study was to examine the differences in age and sex to the histological grading of low-grade and high-grade colorectal adenocarcinoma. This analytical descriptive study used 65 samples of formalin-fixed paraffin-embedded (FFPE) from patients diagnosed with colorectal adenocarcinoma based on histopathological examination with Hematoxylin-Eosin staining, period 2014 to 2016. Data obtained for age, age group < 45 years 12 samples (18.5%), 36 samples in the 45-65 age group (55.4%), and 17 samples in the 65-year age group (26.2%). For sex, 36 samples (55.4%) and 29 samples (44.6%) were female. For the histological grade of low-grade colorectal adenocarcinoma, 43 samples (66.2%) and high-grade 22 samples (33.8%). The data were then analyzed using the Chi-square test, age against the degree of histology obtained p-value of 0.383 (p>0.05), for sex to the degree of histology obtained p-value of 0.338 (p>0.05). The conclusion there are no statistically significant differences between age and sex to histological grades of low-grade and high-grade colorectal adenocarcinoma.
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