Clinicopathological Characteristics of high and low-grade Ovarian Serous Carcinoma
Keywords:serous carcinoma, ovary, characteristics, metastases
Ovarian cancer is the third most common gynecologic malignancy worldwide, after cervical cancer and endometrial cancer, but it has the highest mortality-to-incidence ratio of the three, indicating that it is fatal. Serous carcinoma is divided into two subtypes: low-grade serous carcinoma (LGSC) and high-grade serous carcinoma (HGSC). The purpose of this descriptive study is to determine the clinical characteristics of LGSC and HGSC patients based on five parameters: age, patient's chief complaint, tumor location, FIGO staging, and metastasis. For the period January 2017 to December 2021, 167 samples were collected based on histopathological data from three anatomical pathology laboratories in Makassar, consisting of 47 LGSC samples and 120 HGSC samples. The findings revealed that the most common age in LGSC and HGSC was 40-60 years (70.21% in LGSC and 70.83 percent in HGSC), and the most common chief complaint was abdominal enlargement (95.74% in LGSC and 94.17% in HGSC). LGSC is most commonly unilateral (53.20%), stage I-II (57.45%, and not metastatic (59.57%). In HGSC, it was most commonly bilateral (55%), 82 (68.33%) were diagnosed at stage III-IV, and most had metastases to the omentum (62.50%). In both types of tumors, the omentum is the most common site of tumor metastasis.
Keyword : serous carcinoma, ovary, characteristics, metastasis
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