Antimicrobial Photodynamic Therapy

  • Alaa Hussein Almola Department of Biology, College of Sciences, University of Mosul, Mosul-IRAQ.
  • Amina G.O. Al-Ani Department of Biology, College of Sciences, University of Mosul, Mosul-IRAQ.
  • Sura M.Y. Al-Taee Department of Biology, College of Sciences, University of Mosul, Mosul-IRAQ.
Keywords: Photodynamic therapy, Mechanisms, Photosensitizing, Photodynamic reaction


Photodynamic therapy PDT has appeared in recent years as a non –surgical method for the treatment of cancer and many inflammatory conditions resulting from infection with bacteria, fungi, or viruses and in this side known as Antimicrobial Photodynamic Therapy .This treatment is an oxygen-depending photochemical reaction and occurs as are a result of activating photosensitive compound which leads to the production of cytotoxic oxygen types mostly O2 (singlet oxygen). PDT system composed of three ingredients: light source, photosensitizers and oxygen. PDT can be used in periodontal pocket treatment in order to avoid the use of antibiotics and their side effect as well as reduce the emergence of resistant strains. The application of PDT are in continuous progress and the future of PDT is bright and promising more development especially in the treatment of cancer and many inflammatory disease such as wound and periodontal infection. So, this review aims to explain the mechanism of action and their role in the treatment of the inflammatory injuries.


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