Clinical Investigation of Leprosy Case in Kendari City

Authors

  • Amiruddin Eso Department of Biomedical Science, Faculty of Medicine, Halu Oleo University, Kendari
  • Wa Ode Salma Department of Nutrition Science, Faculty of Public Health, Halu Oleo University, Kendari, Indonesia
  • Ela Martisa Department of English Literature, Halu Oleo University, Kendari, Indonesia
  • Adius Kusnan Department of Nursing, Faculty of Medicine, Halu Oleo University, Kendari, Indonesia
  • Christian Binekada Department of Oncology Surgery, Faculty of medicine, Halu Oleo University, Kendari, Indonesia
  • Jumiati Health Office Staff of Kendari City, Indonesia

Keywords:

Leprosy patient, Kendari City, new case detection

Abstract

Leprosy is a disease caused by Mycobacterium leprae infection that predominantly affects the skin and peripheral nerves. The long term impact of this infection including neuropathy is deformities and disability. The disease is associated with stigma, especially when deformities are present. Majority of patients exposed to Mycobacterium leprous will not develop the disease, suggesting that person immunity plays an important role in disease infection. This study aims to figure out the new case detection of leprosy patient in Kendari city at the year 2017-2019 and to find out the issues in leprosy elimination. The research was an observational study with descriptive approach. Data collection in this study is using the direct interview for the leprosy programmer from all of Public Health Centre in Kendari City and home visiting the leprosy patient.  Data analyzed and presented in narrative and figure. The result showed that in 2019, all of cases (14 cases) detected in the population were adult MB type of leprosy, New Case Detection Rate 3.67/100,000 population. Prevalence rate of leprosy cases that go under treatment in Kendari city was 0.57/10,000 population. Problem in eliminating of leprosy case : Case mapping of leprosy patient was not present, so endemic status not clear; several doctors and programmer of leprosy staffs untrained,  low participation and collaboration of relevant sector.

References

. R. Chou, A. Poobalan, "Guidelines for the Diagnosis, Treatment and Prevention of Leprosy," World Health Organization, vol.1, pp.87, 2017.

. S. Hajar, "Morbus Hansen," Jurnal Kedokteran Syiah Kuala. vol.17, no.3, pp.190–4, 2016.

. F.S de Neves Manta, S.J.M Moreira, L.B.P de Oliveira, R.M.G Garcia, T.A.R Gomides, P.H.F Marçal, et al, "High frequency of M. leprae DNA detection in asymptomatic household contacts," BMC Infectious Diseases. vol.1, no.6, 2018.

. World Health Organization, "Global leprosy update, 2018: moving towards a leprosy- free world," Weekly epidemiological record. 2019;94(30 AUGUST 2019):389–412.

. R. Kurniawan, B. Hardhana, Yudianto. "Data dan Informasi Profil Kesehatan Indonesia 2017". Jakarta: Kementerian Kesehatan RI, 2018.

. C.R. Sigit Prakoeswa, B.B. Rumondor, L. Damayanti, M. Sasmojo, D. Adriaty, M.D. Alinda, et al, "Distribution of Mycobacterium leprae genotypes from Surabaya and Bandung Clinical Isolates by Multiple Locus Variable Number of Tandem Repeat Analysis. Dermatology Reports, Internet : https://www.pagepress.org/journals/index.php/dr/article/view/8017, [Feb.11, 2019].

. E. Valois, E. Ignotti, "Prevalence of Mycobacterium leprae in the environment : A review," Academic Journals, 9(40):2103–10. Available: http://www.academicjournals.org/AJMR%0AAfrican [2015]

. F. Ramona, S. Prakoeswa, "LEPROSY: An OVERVIEW OF EPIDEMIOLOGY AND RISK FACTOR IN INDONESIA," vol.6, no.6, pp.991–5, 2017.

. D. Partogi, D.A Dalimunthe, C.P Hazlianda, "A Study of Selenium in Leprosy," Open Access Macedonian Journal of Medical Sciences.vol.6, no.3, pp.485–7, 2018.

. R.M. Bhat, C. Prakash, "Leprosy: An Overview of Pathophysiology," Interdisciplinary Perspectives on Infectious Diseases, pp.1–6, 2012.

. S. Araujo, L.O. Freitas, L.R. Goulart, I. Maria, B. Goulart, "Molecular Evidence for the Aerial Route of Infection of Mycobacterium leprae and the Role of Asymptomatic Carriers in the Persistence of Leprosy," 63, pp.1412–20, 2016

. R.P. Turankar, S. Pandey, M. Lavania, I. Singh, A. Nigam, J. Darlong, et al, "Comparative evaluation of PCR amplification of RLEP, 16S rRNA, rpoT and Sod A gene targets for detection of M. leprae DNA from clinical and environmental samples," International Journal of Mycobacteriology, vol.4, no.1, pp.54–9, Available: http://dx.doi.org/10.1016/j.ijmyco.2014.11.062 [2015].

. A. Roy, S. Rao, P. Thatkar, A. Sethuraman. "Hansen’s disease in the archipelago," International Journal of Medical Science and Public Health, vol.7, no.11, pp.938, 2018

. M. Lavania, R. Jadhav, R.P. Turankar, I. Singh, A. Nigam, U. Sengupta, "Genotyping of Mycobacterium leprae strains from a region of high endemic leprosy prevalence in India," Infection, Genetics and Evolution, vol. 36, pp. 256–61, Available: http://dx.doi.org/10.1016/j.meegid.2015.10.001 [2015]

. P. Torres, J.J. Camarena, J.R. Gomez, J.M. Nogueira, V. Gimeno, J.C. Navarro, et al, "Comparison of PCR mediated amplification of DNA and the classical methods for detection of Mycobacterium leprae in different types of clinical samples in leprosy patients and contacts," Leprosy review, vol.74, no.1, pp.18–30. Available: http://www.ncbi.nlm.nih.gov/pubmed/12669929 [2003].

. L.É.C, Marques, C.C. Frota, S. Quetz J da, A.H. Bindá, R.M.S. Mota, A. Pontes MA de, et al, "Evaluation of 16S rRNA qPCR for detection of Mycobacterium leprae DNA in nasal secretion and skin biopsy samples from multibacillary and paucibacillary leprosy cases," Pathogens and Global Health, vol.112, no.2, pp.72–8, Available: http://doi.org/10.1080/20477724.2017.1415736 [2018]

. C.K Job, J. Jayakumar, M. Kearney, T.P. Gillis, "Transmission of leprosy: A study of skin and nasal secretions of household contacts of leprosy patients using PCR," American Journal of Tropical Medicine and Hygiene, vol.78, no.3, pp.518–21, 2008.

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Published

2020-01-18

How to Cite

Eso, A., Salma, W. O., Martisa, E. ., Kusnan, A., Binekada, C. ., & Jumiati. (2020). Clinical Investigation of Leprosy Case in Kendari City. International Journal of Sciences: Basic and Applied Research (IJSBAR), 49(1), 119–124. Retrieved from https://gssrr.org/index.php/JournalOfBasicAndApplied/article/view/10619

Issue

Vol. 49 No. 1 (2020)

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Articles

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