|Ali Mohammed Yimer|
|Master of science in inorganic chemistry, Haramaya university|
|The Schiff’s base ligand and its complexes with Ni(II), Cu(II) and Zn(II) were synthesized and characterized by elemental analysis molar conductivity, infrared and ultraviolet-visible spectroscopy and magnetic susceptibility measurements. The ligand, ethylenedianil of o-hydroxyphenylglyoxal, C18H16N2O4, has been synthesized by condensation of ethylenediamine and orthohydroxyphenylglyoxal. The metal complexes were prepared by mixing saturated solutions of ligand and metal salts in appropriate molar ratio in acetone and methanol solvents. The study also confirmed the formation of mono-, di- and trinuclear isopolystructures of the complexes in square planar geometry except for Zn(II) which has tetrahedral stereochemistry. The synthesized ligand and its metal complexes were screened for their antimicrobial activities against two bacterial strains, Staphylococcus aureous and xanthomonas holcicola and two fungal strains, Aspergillus niger and Fusarium oxysporum using disc diffusion method, showing that the complexes were of more antimicrobial activity than the free Schiff’s base.
Key words: antimicrobial studies, disc diffusion method, ethylenedianil of o-hydroxyphenyl glyoxal, ortho-hydroxyphenylglyoxal, Schiff’s base