|Demanding work schedules are a fact of life in modern, 24-hour society. Goods are produced and services are provided all hours of the day and night. This call for people to work odd hours and such work schedules are called shift work. The body has a 24 hour “biological clock” known as circadian rhythm that tells it when to sleep and when to wake up. Sunlight and darkness regulates this clock. Working shifts can affect a worker’s health and safety. Shift work can have many physiological, psychological and social effects on a person. Railway is an important industry where large numbers of human resources are involved in rotational task. The purpose of combining human factor with railway industry workers is to reduce occupational health hazards of the workers. The present study was carried out to assess the work pattern, physiological and psychological cost of work, coping strategies of rotational workers working at reservation counter. The purposive and random sampling design was used to select respondents of reservation counter. A total sample size was 40 in which 24 male and16 female respondents were selected for descriptive and experimental data. The descriptive data was collected with the help of interview schedule through interview method. The experimental data was gathered for different physiological test (blood pressure, heart rate, body temperature) and psychological parameters (letter cancellation, fatigue severity scale). The result reveals that significant difference in physiological parameters i.e. blood pressure, heart rate and psychological test letter cancellation test of the respondents denoting their stress and fatigue due to rotational job demand. As a part of action research a manual and CD entitled Shift Workers Guide for shift workers was prepared. This suggests different guidelines to the individual and organization as how to cope better to the job demand. This would then enhance job satisfaction, health status and lifestyle of the employees at domestic level as well as official front.