Preliminary Results Concerning Investigation of Air Pollution Effect in Western Macedonia on Fasting Blood Glucose During Pregnancy

Itziou A.


Pregnancy is very crucial period in a woman’s life. Several changes occur in her body in order to supply the best to the fetus. During pregnancy glucose metabolism undergoes specific adaptations, including increased hepatic glucose production in the fasting state and maternal peripheral insulin resistance, so that glucose is always supplied to the fetus. PM pollution has recently been suggested as an emerging risk factor for glucose control disorders including impaired glucose regulation, or even diabetes. The aim of the present study was to investigate changes in fasting glucose in pregnant women, associated with changes in exposure to ambient air pollution. 50 pregnant women residents of Kozani, Western Macedonia, Greece participated in the study. The results of the study showed increased levels of fasting blood glucose in most women. Moreover, according to simple linear correlation (Pearson’s test), PM2.5 levels were associated with increased fasting blood glucose. The statistically significant correlation between atmospheric pollution and glucose levels found in the present preliminary study shows a possible role of pollution as a risk factor for second semester glucemia during pregnancy. Therefore future work is considered necessary in order to clarify this possible connection.


pollution; biomarkers; pregnancy; fasting blood glucose.

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