The Benefits of Temu Mangga (Curcuma Mangga Val) in Cognitive Functions of Elderly

N. Saelan Tadjudin, A. Jayalangkara, Andi Asadul Islam, Suryani As’ad, Muh. Nasrum Massi, Ilhamjaya patellongif


The objective of this study was to investigate the benefit of Temu Mangga extract (Curcuma Mangga Val) with cognitive function test using Montreal Cognitive Assesment- Indonesian version (MoCA-Ina -Registry MoCA-Ina / stroke registry-INA 2012) in Elderly. This Clinical trial study was conducted using a double-blind, randomized controlled trial, pre and post-test group design in 85 female participants from Panti Wreda Nursing Home in Jakarta. A total of 83 participants who followed the study to the end. 43 participants were administered the Temu Mangga Capsule (TM) group 3x500 mg/day for 30 days.  Results: Mean score of MoCA-Ina in TM group increased by 2.37 from 23.93 ± 3.73 to 26.30 ± 3.92 with Wilcoxon test p-value = 0.000, and in the control group with 40 participants increased by 2.55 from 23.58 ± 4.60 to 26.13 ± 4.56 with Wilcoxon test p-value = 0.000. Mann-Whitney test results in both groups p > 0.05. Conclusions: There was an increase in each treatment groups and control groups with significant Moca-Ina values, but between the two groups did not show significant difference changes. Psychological factors such as attention and hope will become healthier are a strong factor in this study.


MoCA-Ina; Elderly; Temu Mangga; Cognitive Functions; Nursing home.

Full Text:



. Association AP. The Diagnostic and Statistical Manual of Mental Disorders: DSM 5: bookpointUS; 2013.

. Communications moiaa. Statistic Japan 2012.

. Ananta A, Arifin EN, Bakhtiar. Ethnicity and aging in Indonesia, 2000–2050. Asian Population Studies. 2005;1(2):227-43.

. Association As. 2014 Alzheimer's disease facts and figures. Alzheimer's & Dementia. 2014;10(2):e47-e92.

. Hishikawa N, Takahashi Y, Amakusa Y, Tanno Y, Tsuji Y, Niwa H, et al. Effects of turmeric on Alzheimer's disease with behavioral and psychological symptoms of dementia. Ayu. 2012;33(4):499.

. Nelson L, Tabet N. Slowing the progression of Alzheimer's Disease; what works? Ageing Research Reviews. 2015.

. Schnaider Beeri M, Werner P, Davidson M, Noy S. The cost of behavioral and psychological symptoms of dementia (BPSD) in community-dwelling Alzheimer's disease patients. International journal of geriatric psychiatry. 2002;17(5):403-8.

. Pujimulyani D, Raharjo S, Marsono Y, Santoso U. The Antioxidant Activity and Phenolic Content of Fresh and Blanched White Saffron (Curcuma mangga Val). Jurnal Agritech Fakultas Teknologi Pertanian UGM. 2012;30(02).

. Ono K, Hasegawa K, Naiki H, Yamada M. Curcumin has potent anti‐amyloidogenic effects for Alzheimer's β‐amyloid fibrils in vitro. Journal of neuroscience research. 2004;75(6):742-50.

. Nadia Husein* SL, Yetty Ramli*, Herqutanto** Montreal Cognitive Assessment Version Indonesia (Moca-Ina) For Screening Cognitive Function Disorders.Neuron. 4 Juli 2010; Vol 27 ( Vol 27 ).

. Indonesia Foha. Regulation Of The Minister Of Health Of The Republic Of Indonesia Number 6 Of 2016 About; 2017.

. Al Rasyid I, Syafrita Y, Sastri S. Relationship of Risk Factors with Cognitive Functions in Elderly Sub-District of Padang Panjang Timur Kota Padang Panjang. Journal of Health Andalas.2017;6(1):49-54.

. Hidir A, Aisyah S. Elderly Life Arranged Family at Social House Tresna Werdha Khusnul Khotimah Pekanbaru. Journal Online Student Faculty of Social Science and the Political Science University of Riau. 2014;1(1).

. Colagiuri B, Schenk LA, Kessler MD, Dorsey SG, Colloca L. The placebo effect: from concepts to genes. Neuroscience. 2015;307:171-90.

De la Fuente-Fernández R, Ruth TJ, Sossi V, Schulzer M, Calne DB, Stoessl AJ. Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease. Science. 2001;293(5532):1164-6.

. Fairburn CG, Norman PA, Welch SL, O'Connor ME, Doll HA, Peveler RC. A prospective study of outcome in bulimia nervosa and the long-term effects of three psychological treatments. Archives of general psychiatry. 1995;52(4):304-12.


  • There are currently no refbacks.





About IJSBAR | Privacy PolicyTerms & Conditions | Contact Us | DisclaimerFAQs 

IJSBAR is published by (GSSRR).