2017 Review: Progress in Using Human Stem Cells in the Treatment of Autism Spectrum Disorder

Friedrich K. Weddige

Abstract


Autism and Autism Spectrum Disorders are a set of heterogeneous and enigmatic neurodevelopmental pathologies that arise from a variety of triggers.  In spite of outstanding scientific achievements in the study of the pathologies associated with autism and autism spectrum disorders, as of 2017 these developmental disorders are still without a curative treatment option.  This analysis reviews the therapeutic characteristics of stem cells and how they can provide clinical application and novel treatment options for autism spectrum disorders.  This review integrates a concise evaluation of all stem cell types utilized in autism research and treatment and associates the efficacy, safety, and tolerability findings of the most current stem cell-autism spectrum disorder treatments.  Concluding data outlines budgetary and funding rates associated with stem cell-autism spectrum disorder research (2012-2017) and concludes with avenues for novel research and treatment options.   


Keywords


stem cell; autism; autism spectrum disorder; umbilical cord; stem cell treatment; mesenchymal stem cell.

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