The Relationship Between Propionibacterium Acnes and Free Fatty Acid Levels of the Skin Surface in Acne Vulgaris Patients

Rahmawati Anwar, Farida Tabri, Anis Irawan Anwar, Anni Adriani, Burhanuddin Bahar, Muhammad Nasrum Massi


For a long time hyperseborrhoea has been considered as a major aetiopathogenetic factor for acne. However, emerging data on alterations of sebum lipid composition in acne patients. Indicate that sebum composition may be more important for the development of acne lesions than the secreted amount. Indeed, bacterial hydrolases convert some of the triglycerides to free fatty acids on the skin surface.  Free fatty acids were detected to express proinflammatory and anti-inflammatory properties. The study aims to investigate the relationship between Propionibacterium acnes and free fatty acids at the surface skin of acne vulgaris. The study was conducted at a senior high school in Makassar from July to August 2017. The method is analytic observational with cross-sectional design. The samples are acne vulgaris patients aged between 15 to 18 years old in senior high school of the city. Comedones were taken on acne vulgaris lesion from the 28 samples for the examination of Propionibacterium acnes and sebum using absorbent paper to examine free fatty acid content. The study indicates no significant correlation between free fatty acid from the skin surface of the patients and the presence of Propionibacterium acnes. There is a correlation between Propionibacterium acnes and acne vulgaris but insignificant.


Acne vulgaris; free fatty acids; Propionibacterium acnes.

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