Study of the Fungal Infections Associated with Dermal Infections in Samarra City

Wafaa khalaf Al-mansour, Ghassan. f. Al-samarai, Abdulhanmed. M. Hmoody, Abd alrahman abd. h. Al-marsomi

Abstract


One hundred and ninety two (192) specimen (skin scrapings ,hair and nail) were collected and examined from (192) patients from both sex (110 female and 82 male) after that diagnosed clinically by a specialist doctor as Tinea , and by direct microscopic examination and culture have been diagnosed with dermatophytes one hundred and seventy five (157) patients with rate of (81.11%), . It was clear from the current study, males infection with Tinea was (41.40%) while in females (58.60 %) it was found through the statistical analysis, existence of significant differences at the level of probability (p‹ 0.05). Sources of fungal infection include zoophilic fungi which represent 74(47.13%), followed by Anthropophilic type 45 (28.66%), and Geophilic fungi 38 (24.20%). Dermatophyte species of fungi were isolated from Tinea patients including: Trichophyton rubrum, Trichophyton Mentagrophytes var mentagrophyte,Trichophyton Mentagrophytes var interdigtal, Trichophyton tonsoranse, Trichophyton tonsoranse, Microsporum canis, Epidermaphyton flocosum with different percentage, Candida species were identified by the manual and biochemical methods and we found that the C.albicans, C.tropicalis, C.krusei ,C.parapsilosis and C.glabrata isolated during the study.  And isolation of non dermatophyte isolated during the study : Aspergillus niger, Aspergillus flavus,  Aspergillus versicolar and Penicillium chrysogenum. Also New record of Penicillium vanoranjei in Iraq during the present study.


Keywords


Dermatophyte; Fungal infection; Tinea.

Full Text:

PDF

References


. Waring, P. ;Eichner R.D. ; Mullbacher, A. and Sjaarda, A. (1988).drrmatophyte distirbution Induces Apoptosis in Macrophages Unrelated to Its Antiphagocytic Properties.The Journal Of Biological Chemistry Vol. 263, No. 34, pp. 18493-18499. ©American Society for Biochemistry and Molecular Biology, Inc. USA.

. SC-201299-dermatphyte (2015).Safety Data Sheet .Santa Cruz Biotechnology, Inc. Version 1.1.

. Emmons, C. W.; Binford, C. H.; Utz, J. P. and Kownchung, K. J. (1977). Medical Mycology. 3rd Ed. Lea and Febiger, Philadelphia.

. Council for Agricultural Science and Technology (2003). Mycotoxins: Risks in Plant, Animal and Human Systems. Task Force Report No. 139, Ames, Iowa, USA.

. Chen Y, Zeng H, Tian J, Ban X, Ma B, Wang Y. Antifungal mechanism of essential oil from Anethumgraveolens seeds against Candida albicans. Journal ofMedicinal Microbiology. 2013; 62:1175-1183.

. Chubey BB and Dorrell DC. Changes in the chemical composition of dill oil during hydrodistillation. Canadian Journal of Plant Sciences. 1976; 56:619-622.

. Agarwal, R; Chakrabarti, A; Shah, A; Gupta, D; Meis, JF; Guleria, R; Moss, R; Denning, DW; ABPA complicating asthma ISHAM working, group( 2013). "Allergic bronchopulmonary aspergillosis: review of literature and proposal of new diagnostic and classification criteria". Clinical and experimental allergy: journal of the British Society for Allergy and Clinical Immunology 43 (8): 850–73. International Journal of Sciences: Basic and Applied Research (IJSBAR) (2018) Volume 35, No 3, pp 218-228 227

. Yamazaki M, Fujimoto H, Kawasaki T (1980a) Chemistry of tremorgenic metabolites. I. Fumitremorgin A from dermatophyte. Chem Pharm Bull 28: 245-254 .

. Svahn, K. S.;Ulf Go¨ ransson; , A. ;El-Seedi, H.;Bohlin, L.; Joakim, D.G.;Larsson ; Olsen, B. and .Chryssanthou, E.(2012). Antimicrobial activity of filamentous fungi isolated from highly antibiotic contaminated river sediment. Citation: Infection Ecology and Epidemiology, 2: 11591.

. Richard , J .L. ; Lyon , R.E . ;and Ross , P.F. (1989) . Use of thin layer chromotography for detection and high performance liquid chromatography for quantitiating gliotoxin foom rice cultures of Asergillus fumigatus fresenius . Mycopathologia .107: 145-51 .

. O'Gorman, C.M.; Fuller, H.T. and Dyer, P.S.(2008). Discovery of a sexual cycle in the opportunistic fungal pathogen Aspergillus fumigatus. Nature 457 (7228): 471- 475.

. Nierman, WC; Fedorova, N. (2008)."3rd Advances against aspergillosis. Miami Beach, Florida: Subtelomeric diversity as a major force in evolution of Aspergillus secondary metabolism and virulence pathways"; p. 77.Naseer, M. I., Shupeng, L., & Kim, M. O. (2009). Maternal epileptic seizure induced by pentylenetetrazol: apoptotic neurodegeneration and decreased GABAB1 receptor expression in prenatal rat brain. Molecular Brain, 2, 20.

. Mullbacher, A.; Waring, P. and Eichner R.D. (1985). Identification of an agent in culture of Aspergillus displaying antiphagocytic and immunomodulating activity in vitro. J. Gen Microbiol. 131:1251–1258.

. Mandal ,P.C.and Gupta, P.P. (1993). Experimental aspergillosis in goats: clinical, haematological and mycological studies. Zentralbl Veterinarmed B. 1993 Jun;40(4):283-6 .

. Kosalec, I.; Pepeljnjak S.; and Jandrli, M. (2005).Influence Of Media and Temperature On Gliotoxin Production In Aspergillusfumigatus Strains . Arh Hig Rada Toksikol ; 56:269-273.

. Jussila,J.J. (2003).Inflammatory responses in mice after intratracheal instillation of microbes isolated from moldy buildings. Academic dissertation. Faculty of Pharmacy .University of Kuopio

. Parsaee H, Asili J, Mousavi SH, Soofi H, Emami SA, Tayarani-Najaran Z. Apoptosis induction of Salvia chorassanica root extract on human cervical cancer cell line. Iran J Pharm Res. 2013;12:75–83.

.Iwatsuki,M.;Otoguro,K.;Ishiyama,A.;Namatame,M.;Tukashima,A.N.;Hashida,J.;Nakashima,T.;Masuma,R.;Takahashi,Y.;Yamada,Y.andO¯mura,S.(2010). In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationships The Journal of Antibiotics. 63, 619–622

. Gow, N. A., Van De Veerdonk, F. L., Brown, A. J. and Netea, M. G. 2012. Candida albicans morphogenesis and host defence: discriminating invasion from colonization. Nat Rev Microbiol, 10, 112-22.

. Hmood, B. A. (2015). Detection of gliotoxin in patients with pulmonary mycosis. ISSN 2320-5407 International Journal of Advanced Research (2015), Volume 3, Issue 5, 1467-1476. Journal homepage: http://www.journalijar.com .

. Yamazaki M, Fujimoto H, Kawasaki T (1980a) Chemistry of tremorgenic metabolites. I. Fumitremorgin A from dermatophyte. Chem Pharm Bull 28: 245-254 .

. Zabriskie, J.B. (2009). Essential Clinical Immunology, 1st. ed. Cambridge University Press. UK.


Refbacks

  • There are currently no refbacks.


 

 
  
 

 

  


About IJSBAR | Privacy PolicyTerms & Conditions | Contact Us | DisclaimerFAQs 

IJSBAR is published by (GSSRR).