The Effect of Painless Labor Using Intrathecal Labor Analgesia on Newborns Performance

Nita Ratna Dewanti, Hubertus Oktafandi Purnomo, Husni A Tanra, Dwi Bahagia Febriani, Maisuri Chalid


The oxygen saturation is similar while in ILAs babies have slightly higher non ILAs babies. Even though all of the results doesnt have any significant p value. It conclude that Painless labor using intrathechal analgaesia (ILA) is a safe choice for parturient women with low pain tolerance. Therefore, this will have no effect in neonatal outcomes.

The aim of the study is to examine the safety of painless labor using intratechal labor analgesia in neonatal outcomes. A prospective cohort study of 69 neonates who were born in Bintaro Hospital and Archa Medika Hospital, Indonesia was performed from February to August 2015 Parturient women chose whether they preferred painless labor using ILA to normal delivery without analgesia (NDWA). Fentanly 25ug, bupivacaine 2,5mg, and clonidine 0,045ug were administered as ILA. The neonates were immediately assessed to determine whether they were vigorous or not, followed by Apgar score measurement at one and five minutes after birth, and the changes of oxygen saturation from birth to first ten minutes of life. Results of this study show that a total of 69 neonates were included in the study, of whom 34 babies was born from mother who is received ILA as painless labor, while 35 babies was born from mother without any analgesia. Maternal characteristics including age in addition to neonatal gender and vigorousity may vary but were homogenously distributed both in both groups (ILA and non-ILA groups). Only one baby required resuscitation in pervaginam delivery. Fishers exact test showed no differences between the two groups in vigorousity. Further, no significant differences in Apgar score at first and fifth minute after delivery between both groups. Apgar score in ILAs babies was 10 in all neonates at 10th minute while the mean Apgar score of 9.940.34 in non ILAs babies.


painless labor; intratechal labor analgesia; newborn; oxygen saturation.

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FG, Cunningham. 2001. Maternal adaptation in pregnancy (Mc Graw Hill New York).

J, Littleford. 2005. Avery's Neonatology - Pathophysiology & Management of the Newborn (Lippincott williams & wilkins Philadelphia).

Banks, B. A., N. Stouffer, A. Cnaan, Y. Ning, J. D. Merrill, R. A. Ballard, P. L. Ballard, and Collaborators North American Thyrotropin-Releasing Hormone Trial. 2001. 'Association of plasma cortisol and chronic lung disease in preterm infants', Pediatrics, 107: 494-8.

Ochedalski, T., and A. Lachowicz. 2004. 'Maternal and fetal hypothalamo-pituitary-adrenal axis: different response depends upon the mode of parturition', Neuro Endocrinol Lett, 25: 278-82.

Mears, K., F. McAuliffe, H. Grimes, and J. J. Morrison. 2004. 'Fetal cortisol in relation to labour, intrapartum events and mode of delivery', J Obstet Gynaecol, 24: 129-32.

Smith, A. K., D. J. Newport, M. P. Ashe, P. A. Brennan, J. L. Laprairie, M. Calamaras, C. B. Nemeroff, J. C. Ritchie, J. F. Cubells, and Z. N. Stowe. 2011. 'Predictors of neonatal hypothalamic-pituitary-adrenal axis activity at delivery', Clin Endocrinol (Oxf), 75: 90-5.

Bonnardot, J. P., M. Maillet, J. C. Colau, F. Millot, and P. Deligne. 1982. 'Maternal and fetal concentration of morphine after intrathecal administration during labour', Br J Anaesth, 54: 487-9.

Phillipos, E., A. L. Solevag, G. Pichler, K. Aziz, S. van Os, M. O'Reilly, P. Y. Cheung, and G. M. Schmolzer. 2016. 'Heart Rate Assessment Immediately after Birth', Neonatology, 109: 130-8.

Sivarajan, V. B., and D. Bohn. 2011. 'Monitoring of standard hemodynamic parameters: heart rate, systemic blood pressure, atrial pressure, pulse oximetry, and end-tidal CO2', Pediatr Crit Care Med, 12: S2-S11.

Gajdanowicz, P., E. Michard, M. Sandmann, M. Rocha, L. G. Correa, S. J. Ramirez-Aguilar, J. L. Gomez-Porras, W. Gonzalez, J. B. Thibaud, J. T. van Dongen, and I. Dreyer. 2011. 'Potassium (K+) gradients serve as a mobile energy source in plant vascular tissues', Proc Natl Acad Sci U S A, 108: 864-9.

Wiswell TE. 2011. Resuscitation in the delivery room: lung protection from the first breath., Sep;56(9):1360-7; discussion 1367-8. doi: 10.4187/respcare.01433. Review.

Lu, Y. C., C. C. Wang, C. M. Lee, K. S. Hwang, Y. M. Hua, Y. S. Yuh, Y. L. Chiu, W. F. Hsu, Y. L. Chou, S. W. Huang, Y. J. Lee, and H. C. Fan. 2014. 'Reevaluating reference ranges of oxygen saturation for healthy full-term neonates using pulse oximetry', Pediatr Neonatol, 55: 459-65.

Suwattanaphim, S., S. Yodavuhd, and S. Puangsa-art. 2015. 'Time Duration of Oxygen Adaptation Immediately after Birth; Monitoring by Pulse Oximeter in Perinatal Period of the Infants at Charoenkrung Pracharak Hospital', J Med Assoc Thai, 98: 656-63.

Kokovic, J. T., N. Radunovic, D. Filimonovic, L. Nejkovic, L. Arsenijevic, L. J. Mirkovic, and V. Kokovic. 2015. 'Maternal hemodynamic influence on uteroplacental oxygen distribution during cesarean section', Clin Exp Obstet Gynecol, 42: 610-3.

Koneva, OIu. 2013. '[Interpopulation defferences in parameters of hemocyte DNA-comets of snail Lymnaea stagnalis from regions with the different environmental load]', Tsitologiia, 55: 475-81.


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